isoverbascoside

Isoverbascoside is a phenylpropanoid glycoside and a structural isomer of verbascoside (also known as acteoside). It belongs to the hydroxyphenylethyl glycoside family and contains hydroxytyrosol and caffeic acid moieties linked through a sugar-containing glycosidic framework. Like verbascoside, isoverbascoside is typically described as a natural product found in various plants.

Occurrence and significance: Isoverbascoside has been reported in a range of plant species, often alongside other phenylpropanoid glycosides. It is used in phytochemical studies as part of the verbascoside family to explore biosynthesis, chemotaxonomy, and quality control of plant extracts.

Biological activities: In vitro studies indicate that isoverbascoside exhibits antioxidant activity and free radical scavenging, as well as anti-inflammatory and antimicrobial effects in some systems. The magnitude of activity can depend on the plant source, extraction method, and assay conditions. There are no approved clinical applications for isoverbascoside at this time, and results from laboratory studies require further validation.

Extraction and analysis: Isoverbascoside is typically isolated from plant material by solvent extraction followed by chromatographic purification. Quantification and identification are commonly performed using high-performance liquid chromatography (HPLC) with spectroscopic detection, often in parallel with related compounds such as verbascoside for comparative purposes.

Overall, isoverbascoside is a member of the phenylpropanoid glycoside family with structural and functional similarities to verbascoside, studied mainly in the context of plant chemistry and bioactivity research.