insulinewerking
Insulin action, sometimes referred to in non-English contexts as insulinewerking, denotes the physiological effects produced by insulin. Insulin is a peptide hormone produced by pancreatic beta cells that promotes glucose uptake and utilization in muscle and adipose tissue, suppresses hepatic glucose production, and regulates lipid and protein metabolism. The action of insulin helps maintain blood glucose within a narrow range after meals and during fasting.
Mechanism at the cellular level involves insulin binding to the insulin receptor, a receptor tyrosine kinase,
Pharmacological relevance encompasses differences among insulin formulations. Endogenous insulin and exogenous insulin preparations differ in onset,
Clinical considerations include insulin resistance, a hallmark of type 2 diabetes and metabolic syndrome, which reduces
Research continues to refine understanding of insulin signaling networks and their interactions with other metabolic pathways,