immediateearly
Immediate early genes (IEGs) are a class of genes that are rapidly and transiently activated in response to cellular stimuli, often without the need for new protein synthesis. In neurons and many other cell types, IEGs are among the first genes expressed after activation and frequently encode transcription factors or regulatory proteins that shape subsequent gene expression programs. Their expression is typically detectable within minutes of stimulation and returns to baseline within a few hours.
Activation of IEGs is driven by intracellular signaling pathways triggered by stimuli such as calcium influx,
Functionally, IEGs often encode transcription factors or signaling components that regulate a second wave of gene
In summary, immediate early genes represent a rapid, transient transcriptional response to stimuli, bridging initial signaling