granulátum
Granulátum is a granule, a small, discrete particle formed by agglomerating the particles of a powder or by mechanical compression. In pharmaceutical contexts, granulátum refers to granules used as a dosage form component or as a finished granulated product. The term appears in pharmacopoeias and Latin texts; the plural in Latin is granulāta.
Granulation can be performed by wet granulation, where a liquid binder is added to a blend of
Granulátum typically contains the active pharmaceutical ingredient plus excipients such as fillers, binders, disintegrants, and lubricants.
Key properties include particle size distribution, density, porosity, and flowability; typical granule sizes range from a
Granulátum offers advantages over loose powders: improved flow and compressibility, better content uniformity, reduced dust, and