granulebinding
Granulebinding is a cellular process in which granules, which are membrane-bound or partially enclosed vesicular structures, attach to target membranes or cytoskeletal elements in preparation for communication or effector functions. This binding positions granules for subsequent docking, priming, and fusion, enabling the regulated release of stored cargo such as hormones, neurotransmitters, digestive enzymes, or cytotoxic molecules.
The binding phase is coordinated by a network of proteins that regulate vesicle trafficking and membrane fusion.
Granulebinding occurs in several biological contexts. In endocrine and exocrine systems, secretory granules deliver hormones, enzymes,
Researchers study granulebinding through live-cell imaging, single-granule tracking, and electron microscopy, as well as in vitro