glykyrrhizin

Glycyrrhizin is a triterpene glycoside found in the roots and stems of the licorice plant, Glycyrrhiza glabra. It is the principal active constituent of licorice and is responsible for its sweet taste. Glycyrrhizin is used in various forms, including as a sweetener, a flavoring agent, and in traditional medicine. It has been studied for its potential health benefits, including anti-inflammatory, anti-cancer, and anti-viral properties. However, it is important to note that glycyrrhizin can have side effects, such as high blood pressure and electrolyte imbalances, especially when used in large amounts or over long periods. Therefore, it should be used with caution and under medical supervision. Glycyrrhizin is also known to inhibit the enzyme 11-beta-hydroxysteroid dehydrogenase type 2 (11-beta-HSD2), which is involved in the conversion of cortisol to cortisone. This inhibition can lead to an increase in cortisol levels, which may have adverse effects on the body. As with any supplement or medication, it is recommended to consult with a healthcare provider before using glycyrrhizin.