endotoxintriggered
Endotoxin-triggered refers to physiological and immunological responses initiated by endotoxins, most notably lipopolysaccharide (LPS) found in the outer membrane of Gram-negative bacteria. When endotoxin enters the host, it can provoke a rapid and coordinated inflammatory reaction, ranging from fever and mild inflammation to severe systemic illness.
The primary molecular mechanism involves the recognition of LPS by a receptor complex on immune cells. Lipopolysaccharide
Clinically, endotoxin-triggered inflammation is central to sepsis and septic shock, as well as to sterile inflammatory