dubbelestrengsbreuken
Dubbelestrengsbreuken are breaks that occur in both strands of the DNA double helix. These are considered the most dangerous type of DNA damage because they are difficult for cells to repair accurately. If not repaired properly, they can lead to significant genomic instability, mutations, and cell death.
Several factors can cause dubbelestrengsbreuken. Ionizing radiation, such as X-rays and gamma rays, is a potent
Cells have evolved complex repair mechanisms to deal with dubbelestrengsbreuken. The two main pathways are non-homologous
The proper functioning of these repair pathways is crucial for maintaining genomic integrity. Defects in dubbelestrengsbreuk