difluoroaniline

Difluoroaniline is a chemical compound with the molecular formula C6H5F2N. It is an organic molecule consisting of an aniline ring substituted with two fluorine atoms. The position of the fluorine atoms on the aniline ring can vary, leading to different isomers, such as 2,3-difluoroaniline, 2,4-difluoroaniline, 2,5-difluoroaniline, 2,6-difluoroaniline, 3,4-difluoroaniline, and 3,5-difluoroaniline. These isomers differ in their physical and chemical properties due to the placement of the electronegative fluorine atoms.

Difluoroanilines are typically synthesized through various organic reactions, often involving the fluorination of aniline derivatives or the reduction of difluoronitrobenzene compounds. They are generally colorless to pale yellow liquids or solids, depending on the specific isomer and purity. Their solubility in water is typically low, but they are soluble in many organic solvents.

The difluoroaniline isomers find applications as intermediates in the synthesis of a variety of organic compounds, including pharmaceuticals, agrochemicals, dyes, and polymers. The presence of fluorine atoms can impart unique properties such as increased lipophilicity, metabolic stability, and altered electronic characteristics to the final products. Research continues into exploring new uses for difluoroaniline derivatives in various scientific and industrial fields.