deltavalerolactone

Delta-valerolactone, also known as δ-valerolactone or deltavalerolactone, is a six-membered cyclic ester (a lactone) featuring a single ring oxygen and a carbonyl group. Its structure arises from intramolecular condensation of ω-hydroxycarboxylic acids of suitable chain length, typically HO-(CH2)4-CO2H.

In practice, δ-valerolactone is prepared by lactonization of such ω-hydroxycarboxylic acids or by dehydration of valeric acid derivatives under catalytic conditions. It is a colorless, viscous liquid at room temperature and is miscible with many organic solvents.

Main uses include acting as a solvent for coatings, adhesives, and cosmetics, and as a monomer for biodegradable poly(valerolactone) polymers produced by ring-opening polymerization, often with catalysts such as tin octoate or biocatalysts. The resulting polymer finds applications in medical devices, packaging, and controlled-release systems. δ-Valerolactone is closely related to γ-valerolactone (GVL); both are investigated for biomass-derived chemical routes and as renewable chemical building blocks.

Safety and handling: δ-valerolactone is generally considered to have low acute toxicity, but it can be irritating to eyes and skin and is flammable. Proper handling in a well-ventilated area and away from ignition sources is advised.