deferoksamiini

Deferoxamine is a chelating agent used in medicine. Its primary use is to treat iron overload, a condition where excess iron accumulates in the body, often due to frequent blood transfusions, as seen in conditions like thalassemia. It works by binding to iron molecules in the blood and tissues, forming a stable complex that is then excreted from the body, mainly through urine. This process helps to reduce the toxic levels of iron.

Beyond iron overload, deferoxamine is also employed in the management of aluminum toxicity, particularly in patients with kidney failure who are unable to adequately excrete aluminum. It can help remove excess aluminum from the body. In some cases, it has been investigated for its potential role in treating certain types of fungal infections, although this is not a primary indication.

Deferoxamine is administered intravenously or intramuscularly. Common side effects can include local reactions at the injection site, visual disturbances, auditory changes, and gastrointestinal issues. It is important for healthcare professionals to monitor patients closely during treatment due to the potential for serious adverse reactions. The drug's effectiveness and safety profile necessitate careful consideration of its use in specific clinical situations.