decelularizace
Decellularizace is a process used to remove cells from biological tissues or organs while preserving the extracellular matrix (ECM). The ECM is a complex network of proteins and other molecules that provides structural support and biochemical cues to cells. Decellularization is typically achieved using various physical, chemical, or enzymatic agents. Common methods involve detergents, acids, bases, or enzymes that disrupt cell membranes and lyse cells, releasing their contents. Subsequent washing steps remove the cellular debris.
The primary goal of decellularization is to create a biological scaffold that can be repopulated with a