corticosteroïdesparende
Corticosteroïde-sparing, or corticosteroid-sparing, refers to medical strategies that aim to reduce or avoid the use of systemic corticosteroids (glucocorticoids) while preserving disease control. The approach relies on substituting corticosteroids with alternative therapies or using them at the lowest effective dose. The term corticosteroïdesparende is used in some languages to describe this concept.
Rationale and scope: Prolonged systemic corticosteroid therapy is associated with adverse effects such as osteoporosis, hyperglycemia,
Strategies and agents: steroid-sparing regimens combine non-steroidal therapies that control inflammation, including immunosuppressants (methotrexate, azathioprine, mycophenolate
Evidence and considerations: Efficacy varies by disease; tapering plans are individualized and commonly involve gradual reduction
See also: corticosteroids; steroid-sparing strategies in specific diseases; long-term management of inflammatory diseases.