cisazobenzol

Cisazobenzol, also known as 3,4-dichloro-N-(2-chlorophenyl)-N-methyl-1-azabenzam amide, is a chemical compound that belongs to the class of azabenzamides. It was synthesized in the early 20th century and has been studied for its potential psychoactive and analgesic properties.

Cisazobenzol is a crystalline solid with a white or light yellow color. It has a molecular formula of C12H10Cl3N and a melting point of 118-120°C. The compound is soluble in various organic solvents such as ethanol, ether, and chloroform.

Pharmacological studies have shown that cisazobenzol has sedative and muscle relaxant effects. It has also been found to have analgesic properties, although its mechanism of action is not fully understood. In animal studies, cisazobenzol has been shown to produce a decrease in locomotor activity and an increase in sleep time.

Cisazobenzol has been studied as a potential anxiolytic and anticonvulsant agent, particularly in the 1960s and 1970s. However, its use in humans has been limited due to its potential for side effects, including drowsiness and dizziness. The compound has also been found to have a low safety margin, with a high risk of toxicity at higher doses.

Overall, while cisazobenzol has shown promise as a potential therapeutic agent, its clinical use has been limited due to its potential side effects and toxicity. The compound remains an interesting example of the diverse range of chemical structures and activities that can be found within the azabenzamide class of compounds.