calibrationsplot

A calibrationsplot is a visual representation used in analytical chemistry and other scientific fields to assess the performance of an analytical method. It plots the measured response of an instrument against the known concentrations of a series of standards. These standards, also known as calibration standards or calibrators, are samples with precisely known amounts of the analyte being measured. The plot typically shows a series of points, where each point represents the instrument's response to a specific concentration of the standard.

The primary purpose of a calibrationsplot is to establish a calibration curve, which is a mathematical relationship between the instrument's response and the analyte concentration. This curve allows for the quantitative determination of the analyte in unknown samples. By measuring the instrument's response to an unknown sample and then finding the corresponding concentration on the calibration curve, the amount of analyte present can be accurately determined.

Several factors are assessed from a calibrationsplot. The linearity of the response is crucial; ideally, the instrument should respond proportionally to changes in concentration over the working range. The range of concentrations for which the method is reliable is also important. Additionally, the plot can reveal potential issues such as matrix effects, interferences, or instrumental drift. The quality of the fit of the data points to the chosen mathematical model (e.g., linear regression) is often quantified by statistical measures like R-squared. A well-constructed calibrationsplot with good linearity and a tight fit indicates a reliable analytical method.