bradykininrezeptorblockierende

Bradykinin receptor blockers are a class of drugs used to treat conditions associated with the bradykinin system, which is involved in inflammation and pain. Bradykinin is a peptide that plays a role in various physiological processes, including blood pressure regulation, immune response, and pain sensation. Bradykinin receptor blockers work by inhibiting the action of bradykinin on its receptors, thereby reducing its effects.

These drugs are primarily used to manage symptoms of hereditary angioedema, a rare genetic disorder characterized by recurrent episodes of swelling, often in the face, hands, feet, and gastrointestinal tract. They are also used in the treatment of acute attacks of hereditary angioedema, which can be life-threatening if not promptly treated.

Bradykinin receptor blockers are available in various forms, including tablets, injections, and nasal sprays. The most commonly used drugs in this class include icatibant and lanadelumab. These medications are typically administered as needed for acute attacks or as part of a long-term management plan for chronic conditions.

While bradykinin receptor blockers are effective in managing symptoms of hereditary angioedema, they may have side effects such as headache, nausea, and injection site reactions. As with any medication, it is important to use bradykinin receptor blockers under the guidance of a healthcare professional to ensure safe and effective treatment.