biguanideja
Biguanideja, in English commonly referred to as biguanides, denote a class of organic compounds characterized by two guanidine units linked by a central scaffold. The term is used in pharmacology and antiseptic chemistry to describe both therapeutic drugs and antiseptic agents that share the same basic chemical motif.
In medicine, the most widely known biguanide is metformin, used to treat type 2 diabetes. Its primary
Historically, phenformin and buformin were developed as antidiabetic drugs but were withdrawn in many regions due
In antiseptic practice, biguanides include chlorhexidine and polyhexamethylene biguanide (PHMB). These compounds are used for skin
Safety and side effects: systemic biguanides such as metformin can cause gastrointestinal upset and, rarely, lactic