berotralstat

Berotralstat is a medication used to prevent hereditary angioedema attacks. It is an oral plasma kallikrein inhibitor. Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of swelling in various parts of the body, including the abdomen, face, limbs, and airway. These attacks can be painful and potentially life-threatening if they affect the airway.

Berotralstat works by blocking the action of plasma kallikrein, an enzyme that plays a role in the development of swelling in HAE. By inhibiting this enzyme, berotralstat helps to reduce the frequency of HAE attacks. It is taken once daily.

The effectiveness and safety of berotralstat have been evaluated in clinical trials. Common side effects reported with its use include gastrointestinal issues such as diarrhea, nausea, and abdominal pain. It is important for patients to discuss potential risks and benefits with their healthcare provider. Berotralstat is a prescription medication and should only be used under the supervision of a qualified medical professional. It is not intended for the acute treatment of an HAE attack.