barbituraattien
Barbituraattien, colloquially known as barbiturates, are a class of drugs derived from barbituric acid. They act as central nervous system depressants and were historically widely used as sedatives, hypnotics, anticonvulsants, and anesthetics. Their mechanism of action involves enhancing the effects of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor. This leads to reduced neuronal excitability.
The development of barbiturates began in the late 19th century, with barbital being synthesized in 1902 and
Dependence and withdrawal are serious concerns with barbiturate use. Chronic use can lead to physical dependence,