azatiopriin
Azathioprine, sometimes spelled azatiopriin, is an immunosuppressive medication that is a prodrug of 6-mercaptopurine (6-MP). It is used to reduce immune system activity in various conditions and is available in tablet form for oral administration.
Azathioprine is employed to prevent organ transplant rejection and to treat a range of autoimmune diseases.
Once in the body, azathioprine is converted to 6-MP, which inhibits de novo purine synthesis and can
Azathioprine is typically given orally, with dosing adjusted to the individual and guided by response and tolerance.
Adverse effects and interactions
Common adverse effects include bone marrow suppression (neutropenia, anemia), hepatotoxicity, pancreatitis, nausea, and increased infection risk.