antiDantikroppar
Anti-D antibodies (anti-D-antikroppar) are antibodies directed against the D antigen of the Rh blood group system. They are typically of the IgG class and are formed after exposure to D-positive red blood cells, most often through pregnancy or blood transfusion in individuals who are RhD-negative. These antibodies can cross the placenta and reach fetal red blood cells.
Clinically, anti-D antibodies are most significant in two settings. In pregnancy, maternal anti-D antibodies can cause
Diagnosis involves serologic testing. An antibody screen (indirect antiglobulin test) detects alloantibodies in the patient's serum,