amyloidikertymiä
Amyloid deposits, also known as amyloidosis, refer to the abnormal accumulation of misfolded proteins called amyloids in various tissues and organs. These amyloid proteins, which can originate from different precursor proteins, aggregate into insoluble fibrils that deposit extracellularly. This deposition disrupts normal tissue structure and function, leading to a range of clinical manifestations depending on the affected organ.
The exact mechanisms that trigger amyloid formation are complex and not fully understood. However, it is generally
Amyloidosis can be classified into several types, broadly categorized as primary (AL amyloidosis), secondary (AA amyloidosis),