aminopenicillin
Aminopenicillins are a subclass of penicillin antibiotics that include ampicillin and amoxicillin. They are characterized by an amino substituent on the side chain, which broadens their activity against certain Gram‑negative bacteria compared with natural penicillins while preserving activity against many Gram‑positive organisms.
Like other beta‑lactams, aminopenicillins inhibit bacterial cell wall synthesis by binding to penicillin‑binding proteins, leading to
The usual spectrum includes many Gram‑positive cocci (e.g., Streptococcus species and, in some cases, Enterococcus), plus
Pharmacokinetics differ: amoxicillin has good oral bioavailability and acid stability, with once‑daily or twice‑daily dosing, while
Clinical use includes respiratory tract infections, otitis media, sinusitis, urinary tract infections, and skin infections. Amoxicillin