Williamsonethersyntes
Williamson ether synthesis is a fundamental organic chemical reaction used to create ethers. It involves the reaction of an alkoxide ion with a primary alkyl halide. The alkoxide ion is typically generated by deprotonating an alcohol with a strong base, such as sodium hydride or sodium metal. This nucleophilic alkoxide then attacks the electrophilic carbon atom of the alkyl halide in an SN2 reaction, displacing the halide ion and forming the ether.
The reaction is most effective when using a primary alkyl halide because secondary and tertiary alkyl halides
Williamson ether synthesis is a versatile method for preparing a wide range of symmetrical and unsymmetrical