Veratrumbased
Veratrumbased describes materials derived from Veratrum plants or from alkaloids in the veratrine family. It is used to label extracts, fractions, or synthetic analogs that share the same mechanism of action as veratrine—namely, activation of voltage-gated sodium channels.
Veratridine and related alkaloids bind to sodium channels and cause prolonged activation and delayed inactivation, leading
Historically, veratrumbased preparations were employed as insecticides and, in some regions, as traditional remedies. In modern
Because of their toxicity, veratrumbased materials require strict handling and regulatory controls. They are generally not