VEGFestäjäts
VEGFestäjäts is a hypothetical class of inhibitors targeting vascular endothelial growth factor (VEGF) signaling. The name appears in speculative discussions combining VEGF with the Finnish term estäjä ("inhibitor"), used to describe a theoretical inhibitor of VEGF activity.
In theoretical models, VEGFestäjäts would reduce angiogenesis by one or more mechanisms: sequestering VEGF ligands (VEGF-A,
Challenges include ensuring specificity, avoiding adverse effects on normal vasculature, managing pharmacokinetics and tissue penetration, and
This article describes a hypothetical concept rather than a verified scientific entity.