Uzara

Uzara refers to Xysmalobium undulatum, a shrub native to southern Africa. It belongs to the Apocynaceae family, and the plant’s root has a long history of use in traditional medicine as an anti-diarrheal remedy. In some regions, preparations of uzara root or standardized extracts are sold as over-the-counter products for diarrhea.

The plant grows as a woody shrub with simple leaves and small flowers; the most commonly used medicinal part is the dried root. Traditional preparation methods include grinding the root into powder or making extracts that are then consumed to relieve symptoms of diarrhea and dysentery.

Pharmacologically, uzara contains cardiac glycosides, including bufadienolide-type compounds. These constituents are thought to reduce intestinal motility, contributing to an antidiarrheal effect. Because cardiac glycosides can influence heart function, their presence in uzara means that the plant carries potential risks beyond its gastrointestinal use.

Safety and regulatory notes: Uzara products should be used with caution, especially by people taking cardiac medications or who have heart rhythm disorders, as interactions and toxicity are possible. Reported adverse effects include nausea, vomiting, dizziness, and irregular heartbeat. It is not recommended for use in pregnancy or in young children without medical advice. Users should follow product labeling and consult healthcare professionals if symptoms persist or worsen.