Tumorkifejldéshez

Tumorkifejldéshez is a Hungarian term that translates to "tumor development" or "tumorigenesis" in English. It refers to the complex biological process by which normal cells transform into cancerous cells and begin to proliferate uncontrollably. This process is not a single event but rather a multistep progression driven by accumulated genetic and epigenetic alterations.

The initiation of tumor development often begins with mutations in genes that regulate cell growth, division, and death. These mutations can be caused by various factors, including exposure to carcinogens, radiation, viral infections, or inherited predispositions. When these critical genes are damaged, cells may lose their ability to respond to normal regulatory signals, leading to uncontrolled proliferation.

As the tumor grows, it acquires further genetic changes that enhance its survival, promote its spread (metastasis), and enable it to evade the immune system. This includes mutations in oncogenes, which promote cell growth, and tumor suppressor genes, which normally inhibit it. The tumor microenvironment, consisting of blood vessels, immune cells, and connective tissue, also plays a crucial role in supporting tumor development and progression. Understanding tumorkifejldéshez is essential for developing effective cancer prevention, diagnosis, and treatment strategies.