Tulipalin

Tulipalin is a natural compound classified as a sesquiterpene lactone. It is primarily found in various species of the *Tulipa* genus, commonly known as tulips. The presence of tulipalin is responsible for some of the plant's defense mechanisms against herbivores and pathogens. In humans, tulipalin is known to be a skin irritant and can cause allergic contact dermatitis in individuals who handle tulip bulbs or flowers. This reaction, often referred to as "tulip fingers," is characterized by redness, itching, and blistering. The compound is thought to exert its effects by interacting with skin proteins. While it has been studied for its biological activities, its primary relevance in human interaction stems from its allergenic potential. Research has also explored other potential biological activities of tulipalin, but its irritant properties remain the most well-documented and recognized characteristic.