TranscriptScan

TranscriptScan is a technology used in the field of molecular biology and genomics to analyze and quantify the abundance of RNA in a sample. It is an in vitro enzyme-based method used to measure the RNA content of cells, typically used to study gene expression.

TranscriptScan makes use of a panel of probes that are specific to particular genes or regions of the genome. The RNA in the sample is then converted to complementary DNA (cDNA) using an enzyme called reverse transcriptase. The cDNA is then hybridized with the probes, allowing for the quantification of the abundance of specific transcripts.

The technology allows for the measurement of both the quantity and quality of RNA in a sample. It is commonly used in expression analysis, gene fingerprinting, and in the identification of major RNA transcripts that are present in a sample.

The benefits of TranscriptScan include high sensitivity, rapid analysis time and the ability to analyze a large number of probes per reaction. It is also capable of analyzing both genomic and spliced RNA variants. The sensitivity of the technology means that even low-abundance transcripts can be detected.

The technique is useful in a variety of fields such as biotechnology and medicine. It is used in various research and clinical applications, such as studying the gene expression in cancer cells, in understanding neurodegenerative diseases and in the study of genetic variants that contribute to disease susceptibility.

TranscriptScan is an in vitro technique and therefore does not require living cells to produce the results. The technology provides rapid and sensitive analysis of RNA transcripts and it is an important tool for the study of gene expression.