Teratogenität

Teratogenität refers to the ability of a substance or agent to cause developmental abnormalities in a fetus. These abnormalities, known as birth defects, can range from minor physical malformations to severe internal organ damage or functional impairments. Teratogens can include various factors, such as certain medications, environmental chemicals, infections, and even maternal conditions like uncontrolled diabetes. The timing of exposure during pregnancy is crucial, as different stages of fetal development are sensitive to specific types of teratogenic insults. For instance, exposure during the first trimester, when major organs are forming, is often associated with structural defects. The dose and duration of exposure also play significant roles in determining the severity of the resulting abnormality. Identifying teratogens is vital for public health, allowing for the implementation of preventative measures and informed decision-making regarding medication use and environmental exposures during pregnancy. Medical professionals carefully weigh the risks and benefits of any potential exposure to a pregnant individual.