Szeneszcencia

Szeneszcencia is a term used in biology to describe the process of aging. It refers to the gradual deterioration of functional characteristics in living organisms over time. This decline affects cells, tissues, organs, and ultimately the entire organism, leading to increased susceptibility to disease and eventual death. Szeneszcencia is a complex phenomenon influenced by a combination of genetic and environmental factors. At the cellular level, it involves processes such as telomere shortening, DNA damage accumulation, and the accumulation of senescent cells, which are cells that have stopped dividing but remain metabolically active. These senescent cells can contribute to inflammation and tissue dysfunction. Organismal szeneszcencia manifests as a decrease in physical and cognitive abilities, reduced fertility, and a higher risk of age-related diseases like cancer, cardiovascular disease, and neurodegenerative disorders. While szeneszcencia is a natural part of life, research into its mechanisms aims to understand how to potentially mitigate its negative effects and improve healthspan.