Sulfamide
Sulfamide (systematic name sulfuric diamide) is an inorganic-organic compound with the formula H4N2O2S, often written NH2SO2NH2. It contains the sulfamide functional group, in which two amino groups are bound to a central sulfur atom double-bonded to two oxygen atoms; related substituted derivatives have the general structure R1R2N–SO2–NR3R4. Sulfamide itself is a white crystalline solid with moderate solubility in polar solvents.
Laboratory preparation of sulfamide is commonly achieved by treating sulfuryl chlorides or sulfamoyl chlorides with ammonia,
Sulfamide derivatives are important building blocks in organic and medicinal chemistry. Substituted sulfamides serve as bioisosteres
As a chemical, sulfamide should be handled with standard laboratory precautions; it can be an irritant to