Stemklonen
Stemklonen refers to techniques for generating stem cells that are genetically identical to a donor, enabling research and potentially compatible cell therapies with reduced immune rejection. The term encompasses methods that create pluripotent stem cells similar to those found in embryos, as well as strategies to obtain identical stem-cell lines for a given individual.
There are two main approaches. Somatic cell nuclear transfer (SCNT) creates embryonic-like stem cell lines by
History: The broader concept of cloning was demonstrated in animals in the 1990s. The development of iPSC
Applications include regenerative medicine, disease modeling, and drug screening. Stemklonen-derived cells could potentially replace damaged tissues,
Ethical and regulatory considerations cover issues related to embryo use, donor consent, safety risks such as
Current status indicates clinical use remains limited to research and early trials. Key challenges include differentiation