Skatol

Skatol, also spelled skatole, is an aromatic heterocyclic organic compound in the indole family. Its systematic name is 3-methyl-1H-indole and its chemical formula is C9H9N. It is a volatile, colorless liquid that is notable for its extremely potent odor, which at higher concentrations resembles feces.

Source and occurrence: Skatol is produced biologically by bacterial metabolism of tryptophan in the gut and in decomposing organic matter. It is found in feces, manure, and various decaying materials. Small amounts can be present in some animal secretions and foods.

Biochemical and odor notes: In humans and animals skatole contributes to the characteristic fecal odor of wastes. At trace levels, skatole provides a softer, animalic nuance that is valued in the fragrance industry as part of complex scent profiles, often blended with indole and musk notes.

Uses: In perfumery, skatole is employed as a rare, animalic odorant to add depth and warmth to certain compositions. It is typically used in very low concentrations due to its strong odor. It is also studied as a model compound for odor perception and for understanding degradation products in the environment.

Safety and handling: Skatol is handled as a specialty chemical; its odor is extremely potent and can be irritating to the nose and eyes. Appropriate ventilation and containment are recommended, and exposure should be minimized.