Ser990s

Ser990s refers to a specific amino acid residue at position 990 within a protein sequence. The notation "Ser" indicates the amino acid serine, which is a polar, uncharged amino acid with the chemical formula C3H7NO3. The number "990" denotes its precise location within the primary structure of a protein. The "s" at the end is likely a stylistic choice or part of a specific naming convention within a research context, possibly denoting multiple occurrences or a specific variant.

This particular serine residue can be crucial for protein function. Serine residues are known to participate in various post-translational modifications, such as phosphorylation, glycosylation, and acetylation. Phosphorylation, the addition of a phosphate group, is a common mechanism for regulating protein activity, signaling pathways, and cellular processes. Therefore, the phosphorylation status of Ser990 can significantly impact how the protein interacts with other molecules and carries out its biological role.

Understanding the role of Ser990 often involves studying its modification state in different cellular conditions or in response to specific stimuli. Techniques like mass spectrometry can be used to identify if Ser990 is phosphorylated or otherwise modified. Mutations at this position, replacing serine with another amino acid, can also be engineered to investigate the necessity of this residue for protein function. Depending on the protein and its context, modifications at Ser990 could affect protein folding, stability, enzyme activity, or protein-protein interactions.