Sejtesstromális

Sejtesstromális, also known as stromal cells, refers to a diverse group of cells found within the connective tissue of various organs and tissues in the body. These cells play a crucial role in maintaining tissue architecture, providing structural support, and facilitating communication between different cell types. Stromal cells are not part of the primary functional units of organs, such as neurons in the brain or hepatocytes in the liver, but instead form the supportive framework that surrounds them.

One of the most well-studied types of stromal cells is mesenchymal stem cells (MSCs), which possess the ability to differentiate into multiple cell lineages, including bone, cartilage, and fat cells. These cells are found in bone marrow, adipose tissue, and other locations and have garnered significant interest in regenerative medicine due to their potential for tissue repair and therapeutic applications.

Stromal cells contribute to the extracellular matrix (ECM), a network of proteins and polysaccharides that provides mechanical strength and regulates cellular behavior. They also play a role in immune modulation, wound healing, and the maintenance of homeostasis within tissues. In pathological conditions, such as fibrosis or cancer, stromal cells can become dysregulated, contributing to disease progression.

Research into stromal cells continues to expand, particularly in the fields of stem cell biology, tissue engineering, and cancer biology. Their versatility and influence on tissue function make them a key area of study for understanding both normal physiology and disease mechanisms.