Savalta

Savalta is a brand name for the medication aliskiren. Aliskiren is a direct renin inhibitor, a class of drugs used to treat hypertension, or high blood pressure. It works by blocking the action of renin, an enzyme produced by the kidneys that plays a crucial role in the renin-angiotensin-aldosterone system (RAAS). This system regulates blood pressure and fluid balance. By inhibiting renin, aliskiren reduces the production of angiotensin I and angiotensin II, which are potent vasoconstrictors, leading to a decrease in blood pressure.

Aliskiren is available in tablet form and is typically taken once daily. It can be used alone or in combination with other antihypertensive medications, such as thiazide diuretics, calcium channel blockers, or angiotensin receptor blockers. The effectiveness and safety of aliskiren have been evaluated in numerous clinical trials. Common side effects may include diarrhea, cough, rash, and angioedema. It is important for patients to discuss their medical history and any potential drug interactions with their healthcare provider before starting treatment with aliskiren. Pregnancy and breastfeeding are generally contraindications for its use. Monitoring of kidney function and serum potassium levels is often recommended during treatment.