STXBP1Munc181
STXBP1Munc181 is a protein that plays a crucial role in the regulation of synaptic vesicle trafficking and neurotransmitter release. It is a member of the syntaxin-binding protein (STXBP) family, which includes several proteins involved in the exocytosis of synaptic vesicles. STXBP1Munc181 is specifically known for its interaction with syntaxin 1A (STX1A), a protein that forms a complex with the SNARE proteins to mediate the fusion of synaptic vesicles with the plasma membrane.
The gene encoding STXBP1Munc181 is located on chromosome 17q23.3. Mutations in this gene have been associated
STXBP1Munc181 is expressed in neurons and is localized to the presynaptic terminals. Its function is to regulate
In summary, STXBP1Munc181 is a protein that plays a critical role in synaptic vesicle trafficking and neurotransmitter