SRSF6

SRSF6, also known as SRSF6 or SFRS6, is a protein that in humans is encoded by the SRSF6 gene. This gene is part of the serine/arginine-rich splicing factor (SRSF) family, a group of proteins known to play crucial roles in post-transcriptional gene regulation, particularly in alternative splicing.

The SRSF6 protein functions as an alternative splicing factor. Alternative splicing is a process where a single gene can produce multiple different messenger RNA (mRNA) molecules, leading to the synthesis of different protein isoforms. SRSF6 can bind to specific RNA sequences within pre-mRNAs and influence the inclusion or exclusion of certain exons, thereby directing the splicing outcome.

Research has indicated that SRSF6 is involved in a variety of cellular processes. It has been implicated in cell proliferation, differentiation, and apoptosis. Dysregulation of SRSF6 has been observed in certain cancers, suggesting its potential role as an oncogene or tumor suppressor depending on the cellular context. Its precise mechanisms of action can vary, and it often interacts with other splicing factors and regulatory proteins to fine-tune gene expression. The study of SRSF6 contributes to a broader understanding of how gene expression is modulated beyond transcription.