SDOCTn
SDOCTn, or Spectral-Domain Optical Coherence Tomography nano-enhanced, is a proposed imaging modality that extends conventional SD-OCT by integrating nanoscale light-matter interaction control, ultra-broadband sources, and enhanced computational reconstruction. It envisions achieving higher depth sensitivity and improved axial resolution by exploiting wider spectral bandwidth, more precise dispersion management, and advanced phase-stable detection. The technique relies on spectral-domain interferometry with improved calibration and digital processing to extract sub-nanometer structural information from the interferometric signal and to suppress speckle noise through model-based reconstruction and deep learning.
Potential applications include biomedical imaging where nanoscale features are relevant, such as cellular and subcellular structures
Advantages of SDOCTn would include higher axial resolution, improved sensitivity to weakly scattering features, and non-invasive,