Rotenon

Rotenon is not a widely used or standardized term in scientific references. In most cases, it is a misspelling or variant of rotenone, a naturally occurring pesticide and fish poison. Because the term does not designate a distinct chemical or product, its meaning is determined by context.

Rotenone (spelled rotenone) is derived from plants of the Derris and Lonchocarpus genera. It has historically been used as an insecticide and to remove fish from bodies of water for management purposes. In research, rotenone is used as a mitochondrial complex I inhibitor to study cellular respiration and, in some animal models, to induce Parkinson-like neurodegeneration.

Rotenone is toxic to humans at sufficient exposures and is particularly toxic to aquatic life. Environmental and health concerns have led to increased regulation and restrictions on its use in many countries. Degradation in sunlight and aquatic environments reduces persistence, but spills or improper application can have lasting ecological effects.

Users encountering the term rotenon should check the spelling and source; if the topic is intended to be rotenone, consult reliable sources for chemical properties, safety data, and regulatory status.