Ringchromosom
A ring chromosome is a rare chromosomal abnormality where a chromosome forms a closed circular structure instead of maintaining its linear form. This structural variation occurs when both ends of a chromosome fuse together, typically due to breaks at the telomeres—the protective caps at the ends of chromosomes. Ring chromosomes are often associated with deletions of genetic material at the breakpoints, which can lead to various genetic disorders depending on which chromosome is affected.
The formation of a ring chromosome can result from errors during cell division, exposure to certain chemicals,
Symptoms and effects of ring chromosomes vary widely depending on the specific chromosome involved and the
Diagnosis typically involves genetic testing to confirm the presence of a ring chromosome and assess its impact