Riluzole

Riluzole is a medication used to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It is thought to work by reducing damage to nerve cells. Riluzole is not a cure for ALS, but it may help slow the progression of the disease and prolong survival. It is typically taken orally in tablet form.

The effectiveness of riluzole in ALS has been demonstrated in clinical trials. Studies have shown that it can modestly extend survival by a few months. It may also help to delay the need for mechanical ventilation. However, riluzole does not reverse existing nerve damage or restore lost motor function. Its primary benefit is in slowing the rate of decline.

Common side effects of riluzole include nausea, vomiting, diarrhea, headache, dizziness, and fatigue. Less common but more serious side effects can include liver problems and neutropenia (a low white blood cell count). Patients taking riluzole require regular monitoring of liver function. It is important for individuals to discuss potential risks and benefits with their healthcare provider before starting treatment.

Riluzole is generally prescribed by neurologists specializing in movement disorders or neurodegenerative diseases. The dosage and duration of treatment are determined on an individual basis. It is typically taken twice a day. While riluzole is a significant therapeutic option for ALS, ongoing research continues to explore new and more effective treatments for this complex disease.