Relaxin2s

Relaxin2s, also known as relaxin-like factor 2 (RLN2), is a peptide hormone belonging to the relaxin family. This family includes relaxin, insulin-like growth factors, and insulin. RLN2 is primarily known for its roles in reproduction, particularly in female mammals. It is produced by the corpus luteum during pregnancy and is believed to contribute to the remodeling of connective tissues, preparing the body for childbirth. Beyond its reproductive functions, research suggests that RLN2 may also play a role in cardiovascular health, acting as a vasodilator and potentially offering protective effects against fibrosis. Its expression has been observed in various tissues, including the heart, kidneys, and lungs, indicating a broader physiological influence than initially understood. The exact mechanisms by which RLN2 exerts its effects are still under investigation, but it is known to bind to specific relaxin family G protein-coupled receptors. The study of RLN2 is ongoing, with potential therapeutic applications being explored in areas such as heart failure and fibrotic diseases.