Regulanom
Regulanom is a term that has appeared in speculative or theoretical discussions in molecular biology to denote the comprehensive regulatory architecture of an organism’s genome—the full set of regulatory interactions that govern gene expression. Unlike regulon, which refers to a defined group of genes controlled by a common regulator, the regulanom is intended to describe the entire regulatory network, including transcription factors, regulatory elements such as promoters and enhancers, noncoding RNAs, chromatin modifiers, and signaling pathways that influence transcription, RNA processing, and degradation. The concept emphasizes connectivity, modular organization into regulatory circuits, feedback loops, and hierarchical control.
Origin and usage: The term is not widely standardized; in many studies the activities of regulatory networks
Methods and data types: Building a regulanom typically involves integrating data from ChIP-seq, DNase/ATAC-seq, RNA-seq, perturbation
Relevance: A regulanom framework supports understanding how regulatory architectures drive development, adaptation, and disease, and can
See also: regulon, regulome, gene regulatory network, transcription factors, systems biology.