RecQlike
RecQ-like proteins are a family of DNA helicases found in eukaryotes. They are named after the bacterial RecQ helicase, which plays a crucial role in DNA repair and recombination. The RecQ-like family in humans comprises five members: BLM, WRN, RECQL, RECQL4, and RECQL5. These proteins are essential for maintaining genomic stability and are involved in various DNA metabolic processes, including DNA replication, transcription, repair, and recombination.
The conserved domain structure of RecQ-like proteins includes a helicase domain and a RecQ-conserved C-terminal (HRDC)
The precise mechanisms by which RecQ-like proteins function are still being actively researched. However, it is