RanOLEs
RanOLEs are a class of organic compounds that contain at least one carbon-carbon triple bond, also known as an alkyne group, and at least one hydroxyl group (OH). The name "RanOLE" is a portmanteau derived from "radical" and "alkyne" and "alcohol", reflecting its potential reactivity. These molecules are of interest in organic chemistry due to the dual functionality that allows for a wide range of chemical transformations. The alkyne group is known for its participation in addition reactions and cycloadditions, while the hydroxyl group can undergo oxidation, esterification, and etherification, among other reactions. The proximity of these two functional groups can also lead to unique intramolecular reactions, such as cyclizations.
Research into RanOLEs has explored their synthesis through various methods, often involving the introduction of an