RTKgeeneistä
RTKgeeneistä refers to genes associated with RTK signaling pathways. Receptor tyrosine kinases (RTKs) are a large family of transmembrane proteins that play critical roles in cellular processes such as growth, differentiation, survival, and metabolism. Upon binding of specific ligands, RTKs dimerize and autophosphorylate, initiating a cascade of downstream signaling events. These pathways often involve adapter proteins, second messengers, and other kinases, ultimately affecting gene expression and cellular behavior.
Dysregulation of RTK signaling is implicated in a wide range of diseases, most notably cancer. Mutations that