RORH

RORH, also known as Retinaldehyde Dehydrogenase 1 Family Member 1, is an enzyme that plays a role in the metabolism of vitamin A. Specifically, it is involved in the oxidation of retinaldehyde to retinoic acid. Retinoic acid is a crucial molecule for a variety of biological processes, including vision, cell growth, differentiation, and embryonic development.

The enzyme RORH is a member of the aldo-keto reductase superfamily and is found in various tissues throughout the body, with particularly high expression in the liver and retina. Its activity is important for maintaining proper levels of retinoic acid, which is essential for maintaining healthy vision and for the proper development of many organs. Disruptions in RORH function or expression have been linked to certain visual impairments and developmental abnormalities.

Research into RORH continues to explore its precise mechanisms of action and its broader physiological significance. Understanding the role of RORH contributes to our knowledge of retinoid signaling pathways and their impact on health and disease. Its involvement in vitamin A metabolism makes it a target of interest for potential therapeutic interventions related to vision disorders and developmental conditions.